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许钬
许钬
学习/工作经历:

2009.9-2013.6 福州大学,化学基地班,本科
2013.9-2015.6 福州大学,药理学,提前攻博
2015.9-2019.1 福州大学,药物分析学,博士
 
发表文章:
1. Xu H., Wu D., Li C., et al. Label-free colorimetric detection of cancer related gene based on two-step amplification of molecular machine[J]. Biosensors and Bioelectronics, 2017, 90: 314-320. (if=7.780, 一区, Top期刊
2. Xu H., Xue C., Zhang R., et al. Exponential rolling circle amplification and its sensing application for highly sensitive DNA detection of tumor suppressor gene[J].Sensors & Actuators: B. Chemical, 2017, 243: 1240-1247. (if=5.401, 一区, Top期刊)
3. Xu H., Wu D., Zhang Y., et al. RCA-enhanced multifunctional molecule beacon-based strand-displacement amplification for sensitive microRNA detection[J].Sensors & Actuators: B. Chemical, 2018, 258, 470-477. (if=5.401, 一区, Top期刊)
4. Xu H., Zhang Y., Zhang S., et al. Autonomous table-tennis-motion-type DNA machine for the efficient amplification detection of cancer related gene[J]. Sensors & Actuators: B. Chemical. 2019, 281: 1016-1022. (if=5.667, 一区Top期刊
5. Xu H., Jiang Y., Liu D., et al. Twin target self-amplification-based DNA machine for highlysensitive detection of cancer-related gene [J] Analytica Chimica Acta, 2018, 1011: 86-93. (if=4.95, 一区, Top期刊)
6. Xu H., Zhang Y., Zhang S., et al. Ultrasensitive assay based on a combined cascade amplification by nicking-mediated rolling circle amplification and symmetric strand-displacement amplification [J]. Analytica Chimica Acta, 2019, 1047: 172-178. (if=4.95, 一区, Top期刊).
7. Xu H., Wu D., Jiang Y., et al. Loopback rolling circle amplification for ultrasensitive detection of Kras gene[J]. Talanta, 2017, 164: 511-517. (if=4.162, 二区)
8. Xu H., Zhang S., Ouyang C., et al. DNA nanostructures from palindromic rolling circle amplification for the fluorescent detection of cancer-related microRNAs [J]. Talanta, 2019, 192: 175-181. (if=4.244, 二区)
9. Xu H., Zhang R, Li F, et al. Double-hairpin molecular-beacon-based amplification detection for gene diagnosis linked to cancer[J]. Analytical and Bioanalytical Chemistry, 2016, 408(22): 6181-6188. (if=3.431, 二区)
10. Xu H., Wan L., Xu J., et al. HAMPT, a novel quadruple drug combination designed for cancer metastatic chemoprevention: from hypothesis to proof-of-concept[J]. Current Cancer Drug Targets, acceped (if=2.992, 二区,医学)
11. Wang L., Han Y., Xiao S., Xu H.*, Shen Z.*. Reverse strand-displacement amplification strategy for rapid detection of p53 gene[J]. Talanta, 2018, 187: 365-369.
12. Wu D., Xu H.(co-first author), Shi H, et al. A label-free colorimetric isothermal cascade amplification for the detection of disease-related nucleic acids based on double-hairpin molecular beacon [J]. Analytica Chimica Acta, 2016. (if=4.95, 一区)
13. Wan L, Dong H, Xu H., et al. Aspirin, lysine, mifepristone and doxycycline combined can effectively and safely prevent and treat cancer metastasis: prevent seeds from gemmating on soil[J]. Oncotarget, 2015, 6(34): 35157-35172. (if=6.359)
l  Scientific conference abstracts (会议论文摘要)
1. Xu H., Y. Gao, Y. W. Zhu, L Jia*, Formulation, Transdermal Absorption and Penis Relaxation of An Nitric Oxide Donor Drug for its Coating on Condom, International Chinese Symposium on free radical research, Hong Kong,11/2014.
2. Huo Xu, Liyuan Wan, Zaisheng Wu, Lee jia. HAMPT, a novel quadruple drug combination designed for cancer metastatic chemoprevention: from hypothesis to proof-of-concept, the Fourth Annual Conference of Chinese Society of Micro-& Nanoscience and Technology/the 2016 International Conference of Nanobiology and Nanomedicine, Fuzhou, December 7-10, 2016.
3. Huo Xu, Yifan Jiang, Yafeng Zhang, Mengze Sun and Zaisheng Wu*, Label free, sensitive andspecific microRNA detection by using target-initiated palindromic rolling circle amplification, 第十三届全国化学传感器学术会议, 中国桂林, 11月5-8日, 2017.
4. Huo Xu, Lisha Wang, Yifan Jiang, Zhifa Shen, Zaisheng Wu*, Target-triggered assembly of net-like DNA nanostructure for intracellular imaging of biomolecules.中国化学会第十三届全国分析化学年会, 西安, 6月14-17日, 2018.
5. Liyuan Wan, Huo Xu,Yewei Zhu,Ji Ma,Yu Gao, Lee Jia*,highly affective metastasis prevention therapy ,Annual meeting of the pharmacy, NingDe, 7/2014.
6. Liyuan Wan, Huo Xu, Ji Ma, Yewei Zhu, Jichuang Wang, Yingying Xiao, Jingwei Shao, Lee
Jia*. HAMPT, a specific vcombination designed to control key cancer metastatic pathways: in vitro and in vivo evidences for its cancer metastasis chemopreventin. The 2014 AAPS Annual Meeting and Exposition (The AAPS Journal).
7. Yusheng Lu, Ting Yu, Haiyan Liang, Huo Xu, Yewei Zhu, Jichuang Wang, Jingjing Xie, Jianzhong Chen, Yu Gao and Lee Jia*. S-nitrosocaptopril Prevents Cancer Metastasis by Inhibiting Platelet Activation. 2014 Chemical Biology-Nitric Oxide Shanghai International Conference, Shanghai, 7/2014.
8. Yusheng Lu, Ting Yu, Haiyan Liang, Huo Xu, Yewei Zhu, Yaqiong Pang, Jichuang Wang, Jingjing Xie, Liyuan Wan and Lee Jia*. S-nitrosocaptopril Prevents Cancer Metastasis by Inhibiting adhesion of Circulating Tumor Cells to Endothelial Cells. 2014 AAPS Annual Meeting and Exposition, San Diego Convention Center, November 2-6, 2014. Poster Number: T3016.
9. Jianguo Xu, Hongling Li, Zai-Sheng Wu, Huo Xu, and Lee Jia. Application of autonomous DNA nanomachine for ultrasensitive colorimetric sensing of cancer gene. ChinaNano 2015 meeting; Sept. 3-5, Beijing.
 
l  Oral presentation (口头汇报)
1. “临床疾病的早期诊断的新方法”, 第十三届全国化学传感器学术会议, 2017.11, 中国桂林。(优秀口头报告奖)
2. “Formulation, Transdermal Absorption and Penis Relaxation of An Nitric Oxide Donor Drug for Its Coating on Condom”, International Chinese Symposium on free radical research, 2014, Hong Kong.
 
参与项目:
1.       金纳米颗粒比色分析新技术与肺癌基因目视诊断新方法研究(国家自然科学基金面上项目,项目批准号:21275002,63万),已结题,参加
2.       核酸纳米条纹带“一键式”组装及恶性肿瘤基因诊断新方法研究(国家自然科学基金项目,项目批准号:21775024,78万),在研,参加
3.       适体分子与核酸探针在肿瘤转移预防和预警研究中的应用(福州大学人才基金,项目批准号:XRC-1432,300万),在研,参加
 
发明专利:
发明创造名称:一种利用回文锁式探针检测肿瘤生物标志物的方法(已进入实审阶段)
申请号: 201810488595.8  申请日:2018521
申请人:吴再生(导师)、许钬、孙萌泽
荣誉奖项:
²  2018年获宝钢优秀学生奖学金
²  2017年获博士研究生国家奖学金(国家教育部)
²  第十三届全国化学传感器学术会议中获得“优秀口头报告奖”;
²  2016年12月7日-10日筹办中国微米纳米技术学会纳米科学技术分会第四届年会暨“2016”国际纳米生物医学学术会议担任会场组长,获“最佳组织者”荣誉称号与“优秀志愿者”称号;
²  获福州大学二等奖学金1次、三等奖学金2次;
²  通过大学英语(CET-4、CET-6)考试;
²  2011-2012学年福州大学优秀团员;
²  2013年获福州大学优秀毕业论文奖(论文题目:NO供体药物包被安全套的药剂和药理研究);
²  2015年获“福州大学硕士研究生优秀学业一等奖学金”;
²  2015年获“2015级全日制非定向博士研究生优秀新生奖学金”;
²  2015年11月30日获福建省辐射环境监测站颁发的“辐射安全与防护培训合格证书”;
²  2016年获“福州大学博士生专项助研奖学金”;
²  2018年获福州大学博士研究生助研奖;
²  福州大学博士研究生中期优秀学业一等奖学金
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